Dr. Özlem Yilmaz' Laboratory
Oral Health Sciences Department
Dr. Özlem Yilmaz' laboratory focuses on oral opportunistic bacteria and host interactions. Her lab is particularly interested in the molecular aspects of a major pathogen, Porphyromonas gingivalis in intra-epimucosal colonization in gingiva using advanced human primary cell culture systems and transgenic mice-models. Dr. Yilmaz' lab is one of the few research teams in the US dedicated to uncovering the complex interplays between host and periodontal bacteria in the context of microbial symbiosis as well as pathophysiology of the oral cavity and other systemic locations.
Check Out Our Feature on NIH!
Our work was selected as one of the images in the the NIH Research Image Gallery.
Dr. Yilmaz became an Overseas Fellow of the Royal Society of Medicine, England
Dr. Özlem Yilmaz was inducted as an Overseas Fellow of the Royal Society of Medicine, England in 2017. The Society promotes the exchange of information on science, practice and medicine.
Ayana Paul graduated PREP, and has entered into Emory Microbiology PhD Program
Ayana Paul completed her Post-Baccalaureate Research Education Program (PREP) as part of the 2021-2022 cohort, and will pursue her PhD in Microbiology/Molecular Genetics at Emory University.
Bridgette Wellslager was awarded NIH NRSA F31 Pre-Doctoral Grant
Congratulations to Bridgette Wellslager, a PhD Candidate, who was recently awarded the prestigious F31 Predoctoral Individual National Research Service Grant from NIDCR.
Jaden Lee received first place in the 2022 AADOCR Hatton Competition
Jaden Lee, a DMD/PhD candidate, won first place in the AADOCR Hatton Competition for his novel research presentation. He will be presenting at the 2022 IADR Hatton Competition in China.
JoAnn Roberts was awarded NIH NRSA F31 Pre-Doctoral Grant
Congratulations to JoAnn Roberts, a PhD Candidate, who was recently awarded the prestigious F31 Predoctoral Individual National Research Service Grant Award from the NIDCR.
Jaden Lee was consecutively awarded the prestigious AADR Student Research Fellowship
Jaden Lee, a DMD/PhD candidate, won the AADR Student Research Award two consecutive years (2017-2018) to support his research project and participate in the next AADR meeting.
Bridgette Wellslager was awarded AADOCR Student Research Day
Congratulations to Bridgette Wellsalger, a PhD Candidate, who was recently awarded the prestigious 2023 AADOCR Student Research Day Award from MUSC.
Jaden Lee was awarded NIH NRSA F30 Pre-Doctoral Grant
Congratulations to Jaden Lee, DMD/PhD candidate in our lab! Jaden was recently awarded an NIH F30 Predoctoral Individual National Research Service Award from NIDCR.
Microbes and Infection: Special Issue
In July 2015, Dr. Yilmaz edited a special issue in Microbes and Infection, Institut Pasteur, that focuses on oral pathogens and microbiome in health and disease.
JoAnn Roberts received a scholarship to study redox biology in Karolinska Institutet
JoAnn Roberts, a PhD candidate, was granted a scholarship to study redox biology in Summer 2017 at the Karolinska Institutet in Sweden.
Recent Selected Publications
Patel S, Howard D, Chowdhury N, Derieux C, Wellslager B, Yilmaz O, and French L (2021). Characterization of human genes modulated by Porphyromonas gingivalis highlights the ribosome, hypothalamus, and cholinergic neurons. Front Immunol. 12:646259. doi: 10.3389/fimmu.2021.646259
Lee, JS, Yilmaz, O (2020). Key Elements of Gingival Epithelial Homeostasis upon Bacterial Interaction. Invited Review, Critical Reviews in Oral Biology & Medicine Section. Journal of Dental Res. Nov 17;22034520973012. doi: 10.1177/0022034520973012.
Lee, JS, Chowdhury N, Roberts, JS, and Yilmaz O (2020). Host surface ectonucleotidase-CD73 and the opportunistic pathogen, Porphyromonas gingivalis, cross-modulation underlies a new homeostatic mechanism for chronic bacterial survival in human epithelial cells. Virulence. 11:414-429. doi: 10.1080/21505594.2020.1763061.
Lee J, Spooner R, Chowdhury N, Pandey V, Wellslager B, Atanasova K, Evans Z, Yilmaz O (2020). In Situ Intraepithelial Localizations of Opportunistic Pathogens, Porphyromonas gingivalis and Filifactor alocis, in Human Gingiva. Current Research in Microbial Sciences. 1, 7-17. doi: 10.1016/j.crmicr.2020.05.001.
Olsen I and Yilmaz O (2019). Possible role of Porphyromonas gingivalis in orodigestive cancers. J Oral Microbiol. Jan 9;11(1):1563410. doi: 10.1080/20002297.2018.1563410. eCollection 2019.
Lee K, Roberts JS, Choi C, Atanasova KR, Yilmaz O (2018) Porphyromonas gingivalis Traffics into Endoplasmic Reticulum-Rich-Autophagosomes for Successful Survival in Human Gingival Epithelial Cells, Virulence April 4:1-26. doi:10.1080/21505594.2018.1454171
Lee JN, Roberts JS, Atanasova KR, Chowdhury N and Yilmaz O (2018) A Novel Kinase Function of a Nucleoside-diphosphate-kinase Homolog in P. gingivalis is Critical in Subversion of Host Cell Apoptosis by Targeting Heat-Shock Protein 27, Cellular Microbiology, Jan 22. doi: 10.1111/cmi.1282.